Disease: Bone Diseases
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
WWTR1 Q9GZV5 WW domain containing transcription regulator 1 Enzyme modulator 0.94 0.529 0.615
WNT1 P04628 Wnt family member 1 Signaling 0.33 0.495 0.769
TNFSF11 O14788 TNF superfamily member 11 Signaling 4.9E-03 0.453 0.846
SPARC P09486 secreted protein acidic and cysteine rich Signaling 0.89 0.445 0.846
SP7 Q8TDD2 Sp7 transcription factor Nucleic acid binding 0.58 0.711 0.462
SOST Q9BQB4 sclerostin 0.87 0.474 0.808
SMAD4 Q13485 SMAD family member 4 Transcription factor 1.00 0.401 0.808
SERPINH1 P50454 serpin family H member 1 Enzyme modulator 2.8E-02 0.545 0.769
SERPINF1 P36955 serpin family F member 1 Enzyme modulator 7.8E-08 0.460 0.846
PTH P01270 parathyroid hormone 1.2E-02 0.397 0.846
PNPLA2 Q96AD5 patatin like phospholipase domain containing 2 Enzyme 4.1E-03 0.511 0.846
PLS3 P13797 plastin 3 Cellular structure 0.99 0.656 0.500
P3H1 Q32P28 prolyl 3-hydroxylase 1 Extracellular structure 2.3E-20 0.736 0.231
MIR29B2 microRNA 29b-2 0.484 0.885
MIR29B1 microRNA 29b-1 0.485 0.846
LRP6 O75581 LDL receptor related protein 6 0.70 0.536 0.808
LRP5 O75197 LDL receptor related protein 5 0.51 0.485 0.846
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
GH1 P01241 growth hormone 1 Signaling 3.0E-02 0.373 0.923
FGFR3 P22607 fibroblast growth factor receptor 3 Kinase 1.6E-05 0.391 0.846
DMD P11532 dystrophin 1.00 0.423 0.923
CXCR4 P61073 C-X-C motif chemokine receptor 4 G-protein coupled receptor 1.8E-02 0.362 0.923
CRTAP O75718 cartilage associated protein Extracellular structure 5.5E-04 0.636 0.654
COL1A1 P02452 collagen type I alpha 1 chain 1.00 0.430 0.808
BMP1 P13497 bone morphogenetic protein 1 8.9E-04 0.554 0.769